In this article, I will discuss the Best Cross-Chain Wallets with Ledger Support. With Ledger integration, these wallets allow users to manage multiple cryptocurrencies across various blockchains.
They also seamlessly link to Ledger hardware wallets, providing an extra layer of security. Whether you’re into DeFi, NFTs, or multi-chain investing, knowing these wallets can enhance your asset protection strategies while streamlining cross-chain transactions.
Key Point & Best Cross-Chain Wallets with Ledger Support List
| Wallet Name | Key Point |
|---|---|
| MetaMask | Popular Ethereum-based wallet with cross-chain support via custom networks. |
| Rabby Wallet | Security-focused wallet with Ledger integration and transaction simulation. |
| XDEFI Wallet | Multi-chain wallet optimized for DeFi and NFTs with hardware wallet support. |
| Trust Wallet | User-friendly mobile wallet supporting 70+ blockchains and Ledger devices. |
| Keplr Wallet | Best for Cosmos ecosystem with Ledger support and interchain capabilities. |
| Leap Wallet | Focused on Cosmos chains, offering smooth staking and Ledger integration. |
| Zerion Wallet | DeFi smart wallet with portfolio tracking and Ledger compatibility. |
| Guarda Wallet | Non-custodial wallet supporting 50+ blockchains with Ledger connection. |
| MyEtherWallet (MEW) | Veteran Ethereum wallet with strong Ledger integration and dApp access. |
| Enkrypt Wallet | Polkadot and EVM-compatible wallet with cross-chain support and Ledger use. |
1.MetaMask
MetaMask is one of the best cross-chain wallets with Ledger integration because of how deeply woven it is into Web3 and its network flexibility. What makes MetaMask truly special is the possibility to add EVM-compatible chains manually, which permits users to access assets on different blockchains.

Coupled with using a Ledger hardware wallet for increased security, offline transaction approval adds automated account interaction via dApps or DeFi protocols across all networks through a single interface.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports multiple EVM-compatible blockchains via custom networks. |
| Ledger Integration | Fully compatible with Ledger hardware wallets for secure transaction signing. |
| KYC Requirement | Minimal to no KYC required for wallet usage; self-custodial. |
| User Control | Users retain full control of private keys through Ledger device. |
| dApp Compatibility | Wide compatibility with decentralized applications across networks. |
| Security | Hardware wallet connection adds an extra layer of protection. |
| Network Customization | Easily add and switch between various blockchain networks. |
| Interface | Intuitive browser extension and mobile app available. |
2.Rabby Wallet
Rabby Wallet is among the best cross-chain wallets featuring Ledger support. The wallet stands out for its convenience in catering to multi-chain DeFi users. One exceptional feature is automatic network switching depending on which dApp you are using, saving users a lot of time.

Built-in transaction simulation allows users to preview potential outcomes before confirming, adding an extra safety layer that is unique compared to other wallets. Moreover, native ledger device support maximizes güvenlik key management while maintaining smooth interaction across Ethereum and other EVM compatible blockchains.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports multiple EVM-compatible blockchains seamlessly. |
| Ledger Integration | Native support for Ledger hardware wallets for secure transaction signing. |
| KYC Requirement | Minimal to no KYC needed; fully non-custodial wallet. |
| Security | Transaction simulation and auto network switching enhance safety. |
| User Control | Users maintain full control over private keys via Ledger device. |
| dApp Compatibility | Compatible with major decentralized applications across chains. |
| Automatic Network Switch | Switches networks automatically based on the connected dApp. |
| Interface | User-friendly browser extension focused on security and ease of use. |
3.XDEFI Wallet
XDEFI Wallet ranks as one of the best cross-chain wallets with Ledger support owing to its true multi-chain architecture supporting more than 30 blockchains natively and including Bitcoin, Ethereum, and Cosmos ecosystems.

Its distinct features include auto-detection of assets and smart routing by chains which permit toggling on network and off network free token management. Users can access DeFi, NFTs, or any cross-chain tools through an all-in-one interface while enjoying full control over signing transactions because of XDEFI Wallet’s integration with Ledger, enhancing security during use.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports 30+ blockchains including EVM, Bitcoin, Cosmos ecosystems. |
| Ledger Integration | Full Ledger hardware wallet compatibility for secure key management. |
| KYC Requirement | Minimal to no KYC required; non-custodial wallet. |
| Security | Hardware wallet support combined with built-in transaction safety features. |
| User Control | Users retain private keys securely via Ledger device. |
| Auto Asset Detection | Automatically detects assets across supported chains. |
| Chain Routing | Intelligent routing for cross-chain swaps without manual switching. |
| Interface | Unified, multi-chain wallet interface optimized for DeFi and NFTs. |
4.Trust Wallet
Trust Wallet continues to be one of the leading cross-chain wallets that support Ledger devices, boasting an intuitive interface on more than 70 supported blockchains. Its mobile-centric design paired with direct integration with Ledgers make crypto asset management more secure and portable than most other wallets.

Unlike most wallets, Trust Wallet comes equipped with a built-in Web3 browser making dApp participation handy without requiring additional plugins. This mix simplicity, extensive network coverage, and military-grade cryptographic security makes it unparalleled for users managing multiple chains.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports 70+ blockchains including Ethereum, Binance Smart Chain, and more. |
| Ledger Integration | Compatible with Ledger devices for secure transaction signing. |
| KYC Requirement | No mandatory KYC; fully non-custodial wallet. |
| Security | Hardware wallet support plus biometric and PIN protection on mobile. |
| User Control | Users keep full control of private keys; Ledger adds offline security. |
| Built-in Web3 Browser | Allows direct access to decentralized apps without extensions. |
| Multi-Platform | Available on mobile with seamless Ledger hardware wallet connection. |
| Ease of Use | Intuitive interface designed for beginners and experienced users alike. |
5.Keplr Wallet
Keplr Wallet is one of the leading cross-chain wallets with Ledger support tailored for the Cosmos ecosystem and IBC-enabled blockchains. Its distinct benefit is smooth interchain staking and governance participation from a single interface across multiple chains.

The wallet supports direct Ledger integration which permits users to securely log into transactions with full control over their keys. With dozens of networks in the cosmos ecosystem integrated, Keplr provides a cosmos user-focused seamless unarguably secure experience in the growing world of interchain DeFi.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports Cosmos ecosystem and IBC-enabled blockchains. |
| Ledger Integration | Full Ledger hardware wallet compatibility for secure signing. |
| KYC Requirement | Minimal to no KYC; non-custodial wallet. |
| Security | Hardware wallet support ensures offline key security. |
| Interchain Staking | Enables staking across multiple Cosmos chains easily. |
| Governance Participation | Users can vote on-chain directly via the wallet. |
| User Control | Private keys stored securely on Ledger device. |
| Interface | Clean, user-friendly UI focused on Cosmos network users. |
6.Leap Wallet
Leap Wallet is among the best cross-chain wallets that support Ledger. It aims to enhance user experience within the Cosmos ecosystem. Its best feature is leap’s advanced staking tools which come with rewards tracking and validator insights in real time, perfect for those who are deeply engaged in the network.

With native spacer support leap works perfectly with mounted ledger devices enabling users to sign transactions while using different chains in Cosmos. Other than offering robust security and precision for multi-chan assets, it uses powerful native facilitites supporting interchain swaps and governance.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports multiple Cosmos-based blockchains. |
| Ledger Integration | Compatible with Ledger devices for secure transaction signing. |
| KYC Requirement | Minimal to no KYC; fully non-custodial wallet. |
| Security | Hardware wallet support ensures offline private key safety. |
| Advanced Staking Tools | Real-time rewards tracking and validator insights. |
| Interchain Swaps | Enables seamless token swaps across Cosmos chains. |
| User Control | Private keys remain secure on Ledger hardware. |
| Interface | Intuitive UI designed for Cosmos ecosystem users. |
7.Zerion Wallet
Zerion Wallet is known as one of the best cross-chain wallets with Ledger support, owing to its focus on DeFi portfolio management across several blockchains. What distinguishes Zerion is its singular unified interface that automatcalily sums up and displays all assets, NFTs, and DeFi holdings from multiple chains into a single dashboard.

Users with a Ledger device can connect it directly and manage their holdings while monitoring them with hardware-level security. For security-conscious DeFi investors, this blend of comprehensive asset inspection along with cross-chain functionality makes Zerion perfect.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports multiple EVM-compatible blockchains. |
| Ledger Integration | Full compatibility with Ledger for secure transaction signing. |
| KYC Requirement | Minimal to no KYC; non-custodial wallet. |
| Security | Hardware wallet connection ensures offline key safety. |
| DeFi Portfolio Tracking | Aggregates assets, NFTs, and DeFi positions in one dashboard. |
| User Control | Users retain full control of private keys via Ledger. |
| Interface | Clean, unified dashboard optimized for DeFi users. |
| Built-in Swap | Allows cross-chain token swaps directly within the wallet. |
8.Guarda Wallet
Guarda Wallet is one of the few cross-chain wallets with Ledger integration, making it easy to use Guarda’s non-custodial wallet for over 50 blockchains. What makes Guarda shine above other wallets is their integration of Ledger devices that helps the user manage private keys using offline vaults.

Moreover, interface on mobile, desktop, and through the web makes it easier for user’s to access their account and use built-in exchange and staking services without losing cryptocurrency hardware wallet protection.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports 50+ blockchains including major networks. |
| Ledger Integration | Fully compatible with Ledger devices for secure signing. |
| KYC Requirement | Minimal to no KYC; non-custodial wallet. |
| Security | Hardware wallet support ensures private keys stay offline. |
| Multi-Platform | Available on desktop, mobile, and web platforms. |
| Built-in Exchange & Staking | Integrated exchange and staking features within the wallet. |
| User Control | Users maintain full control of their private keys. |
| Interface | Simple and intuitive interface for managing diverse assets. |
9.MyEtherWallet (MEW)
MEW (MyEtherWallet) is arguably one of the best multi-chain wallets that offers Ledger support. It specializes on Ethereum and EVM compatible networks. Its distinctive advantage is providing a fully open-source interface where users can connect their Ledger devices for offline key management securely.

MEW directly supports access to decentralized applications and DeFi protocol, supporting numerous chains based off Ethereum which make it cost-effective for security-minded users to utilize cross-chain functionality.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports Ethereum and multiple EVM-compatible networks. |
| Ledger Integration | Full Ledger hardware wallet compatibility for secure signing. |
| KYC Requirement | Minimal to no KYC; fully non-custodial wallet. |
| Security | Hardware wallet connection ensures private keys remain offline. |
| dApp Access | Direct integration with decentralized applications and DeFi protocols. |
| User Control | Users retain full control of private keys via Ledger. |
| Open Source | Fully open-source platform for transparency and security. |
| Interface | User-friendly web and mobile interface focused on Ethereum users. |
10.Enkrypt Wallet
Among the best cross-chain wallets with Ledger support, Enkrypt Wallet focuses on Polkadot and other EVM-compatible chains. Its seamless integration with the Polkadot ecosystem is a unique advantage for users as they can manage parachain assets and Ethereum tokens in one secure interface.

With Ledger support, Enkrypt keeps private keys offline during transactions which secures borders on DeFi and NFT activities while maintaining top security—this ease of access makes it a leading choice for users operating in multi blockchain environments.
| Feature | Details |
|---|---|
| Cross-Chain Support | Supports Polkadot, Ethereum, and other EVM-compatible chains. |
| Ledger Integration | Compatible with Ledger devices for secure transaction signing. |
| KYC Requirement | Minimal to no KYC; fully non-custodial wallet. |
| Security | Private keys remain offline through Ledger hardware support. |
| Polkadot Ecosystem | Native support for managing parachain assets and staking. |
| User Control | Users maintain full control over their private keys. |
| Interface | Clean, intuitive UI designed for multi-chain asset management. |
| Cross-Chain Functionality | Enables easy access to DeFi and NFT activities across supported blockchains. |
Conclusion
To summarize, considering best cross-chain wallets with Ledger support, a user with Metamask. Rabby, XDEFI and other supported wallets reap the benefits of offline key management by leveraging Ledgers powerful features including effortless network swap DeFi engagement alongside integrated UX design Lazers serving as backbone to unbriddled on chain interfacing.
Choosing the right crypto held depends on your blockchained needs but integrating ledger support provides unshakable protection












































